Æ»¹ûÒùÔº

Updated: Sun, 10/06/2024 - 10:30

From Saturday, Oct. 5 through Monday, Oct. 7, the Downtown and Macdonald Campuses will be open only to Æ»¹ûÒùÔº students, employees and essential visitors. Many classes will be held online. Remote work required where possible. See Campus Public Safety website for details.


Du samedi 5 octobre au lundi 7 octobre, le campus du centre-ville et le campus Macdonald ne seront accessibles qu’aux étudiants et aux membres du personnel de l’Université Æ»¹ûÒùÔº, ainsi qu’aux visiteurs essentiels. De nombreux cours auront lieu en ligne. Le personnel devra travailler à distance, si possible. Voir le site Web de la Direction de la protection et de la prévention pour plus de détails.

Thomas M.S. Chang

Academic title(s): 

Emeritus Professor, Physiology; Professor, Department of Biomedical Engineering

Thomas M.S. Chang
Contact Information
Address: 

Department of Physiology
Æ»¹ûÒùÔº
McIntyre Medical Sciences Building,
Room 1004
3655 Promenade Sir William Osler
Montréal, Québec H3G 1Y6

Email address: 
artcell.med [at] mcgill.ca
Phone: 
(514) 398-3512
Department: 
Biomedical Engineering
Physiology
Area(s): 
Artificial Cells and Organs
Molecules and Materials
Degree(s): 

M.D., Ph.D., Æ»¹ûÒùÔº

Current research: 

Artificial cells in biotechnology and medicine with emphasis on potential applications in medicine

Chang is credited with inventing microencapsulation, the technique that enables functional biochemical to be held inside artificial membranes so they can emulate both in-vitro and in-vivo the behaviour of some natural cells. "Artificial cells" already have many medical applications.They are used in cases of chronic renal failure, drug poisoning, liver failure, enzyme therapy and metabolic function replacement.Ìý

Chang's group is working with artificial cells filled with enzymes. They convert waste products such as ammonia and urea into the essntial amino acids valine, leucine and isoleucine which also hold promise as a treatment of enzyme-deficiency diseases such as phenylketonuria (PKU) that could process the damaging phenylalanine and remove it from the system.Ìý

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Selected publications: 

Full text of monographs, videos, editorials and most recent papers are available onÌý

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