/newsroom/taxonomy/term/2826/all en /newsroom/channels/news/discovery-reveals-blocking-inflammation-may-lead-chronic-pain-339532 <p>Using anti-inflammatory drugs and steroids to relieve pain could increase the chances of developing chronic pain, according to researchers from 苹果淫院 and colleagues in Italy. Their research puts into question conventional practices used to alleviate pain. Normal recovery from a painful injury involves inflammation and blocking that inflammation with drugs could lead to harder-to-treat pain.</p> Tue, 10 May 2022 17:33:06 +0000 shirley.cardenas@mcgill.ca 288132 at /newsroom /newsroom/channels/news/sex-bias-pain-research-322305 <p>It is increasingly clear that male and female humans and rodents process pain in different ways. And that there are important differences in the underlying mechanisms involved at genetic, molecular, cellular, and physiological levels. Despite this fact, according to a review paper from 苹果淫院 published today in <a href="https://www.nature.com/articles/s41583-020-0310-6"><i>Nature Reviews Neuroscience</i></a>, most pain research remains overwhelmingly based on the study of male rodents, continuing to test hypotheses derived from earlier experiments on males.</p> Thu, 21 May 2020 14:04:36 +0000 justin.dupuis@mcgill.ca 212044 at /newsroom /newsroom/channels/news/mcgill-researchers-end-decade-long-search-mechanical-pain-sensor-320743 <p>Researchers at 苹果淫院 have discovered that a protein found in the membrane of our sensory neurons are involved in our capacity to feel mechanical pain, laying the foundation for the development of powerful new analgesic drugs.</p> <p>The study, published in <a href="https://www.cell.com/cell/fulltext/S0092-8674(20)30114-8"><i>Cell</i></a>, is the first to show that TACAN, a highly conserved protein among vertebrates whose function remained unclear, is in fact involved in detecting mechanical pain by converting mechanical pressures into electric signals.</p> Mon, 24 Feb 2020 15:38:07 +0000 justin.dupuis@mcgill.ca 199495 at /newsroom /newsroom/mathieu-roy Fri, 17 Jan 2020 22:42:26 +0000 shirley.cardenas@mcgill.ca 197039 at /newsroom /newsroom/channels/news/men-and-women-remember-pain-differently-293050 <p>Scientists increasingly believe that one of the driving forces in chronic pain鈥攖he number one health problem in both prevalence and burden鈥攁ppears to be the memory of earlier pain. Research published today in <i>Current Biology</i> suggests that there may be variations, based on sex, in the way that pain is remembered in both mice and humans.</p> Wed, 09 Jan 2019 19:25:48 +0000 katherine.gombay@mcgill.ca 130874 at /newsroom /newsroom/channels/news/equality-need-not-be-painful-261722 <p>Pain researchers' arguments for using only male rodents in preclinical pain research don't hold up to scrutiny, says 苹果淫院 neuroscientist Jeffrey Mogil. <a href="http://www.nature.com/nature/journal/v535/n7611_supp/full/535S7a.html#author-information">Nature</a></p> Wed, 13 Jul 2016 18:18:59 +0000 christopher.chipello@mcgill.ca 26017 at /newsroom /newsroom/channels/news/antidepressants-rise-label-prescriptions-260949 <p><strong><em><a href="/newsroom">苹果淫院 Newsroom</a></em></strong></p> <p>Antidepressant use in North America has increased over the last 2 decades. A suspected reason for this trend is that primary care physicians are increasingly prescribing antidepressants for nondepressive indications, including unapproved (off-label) indications that have not been evaluated by regulatory agencies.</p> Tue, 24 May 2016 13:45:21 +0000 nima.adibpour@mail.mcgill.ca 25875 at /newsroom /newsroom/channels/news/brighter-prospects-chronic-pain-260515 <p><span>The potential of light as a non-invasive, highly-focused alternative to pain medication was made more apparent thanks to research conducted by scientists at the Montreal Neurological Institute and Hospital of 苹果淫院 and the 苹果淫院 Health Centre.</span></p> Wed, 20 Apr 2016 15:20:57 +0000 laurie.devine@mcgill.ca 25747 at /newsroom /newsroom/channels/news/location-may-be-key-effectively-controlling-pain-258233 <p><em><strong>By Cynthia Lee</strong></em></p> <p><a href="/newsroom/">Newsroom</a></p> <p>In real estate, location is key. It now seems the same concept holds true when it comes to stopping pain. New research published in <em>Nature Communications</em> indicates that the location of receptors that transmit pain signals<em> is</em> important in how big or small a pain signal will be -- and therefore how effectively drugs can block those signals.</p> Mon, 01 Feb 2016 16:44:57 +0000 nima.adibpour@mail.mcgill.ca 25203 at /newsroom /newsroom/jeffrey-mogil Thu, 19 Dec 2019 19:35:06 +0000 Anonymous 23132 at /newsroom /newsroom/channels/news/quebec-science-honours-three-mcgill-discoveries-257540 <p><em>By Chris Chipello</em></p> <p><img src="/newsroom/files/newsroom/quebecscience_2.jpg" style="width:690px; height:226px" /></p> Wed, 23 Dec 2015 18:43:28 +0000 nima.adibpour@mail.mcgill.ca 25052 at /newsroom /newsroom/channels/news/american-placebo-255973 <p>A new study finds that rising placebo responses may play a part in the increasingly high failure rate for clinical trials of drugs designed to control chronic pain caused by nerve damage. Tue, 06 Oct 2015 16:16:40 +0000 melody.enguix@mcgill.ca 24521 at /newsroom /newsroom/channels/news/his-and-her-pain-circuitry-spinal-cord-253724 <p>New research released today in <em>Nature Neuroscience</em> reveals for the first time that pain is processed in male and female mice using different cells. These findings have far-reaching implications for our basic understanding of pain, how we develop the next generation of medications for chronic pain鈥攚hich is by far the most prevalent human health condition鈥攁nd the way we execute basic biomedical research using mice.</p> <p> Mon, 29 Jun 2015 14:59:48 +0000 christopher.chipello@mcgill.ca 24277 at /newsroom /newsroom/channels/news/new-hope-fight-against-pain-242448 Tue, 17 Feb 2015 16:19:52 +0000 cynthia.lee@mcgill.ca 22092 at /newsroom /newsroom/channels/news/secret-empathy-241112 Thu, 15 Jan 2015 16:52:33 +0000 cynthia.lee@mcgill.ca 21891 at /newsroom