/neuro/taxonomy/term/182/all en /neuro/article/research-neuro-xxceptional/personal-and-scientific-journey-parkinsons-disease Neuroscientist Heidi McBride shares her family history of Parkinson's and what she hopes to accomplish in understanding the disease. Thu, 07 Apr 2022 16:29:10 +0000 Heidi McBride 5415 at /neuro /neuro/channels/news/mitochondria-drive-cell-survival-times-need-270560 <h2>Discovery points to possible target for cancer drugs</h2> <p>Æ»¹ûÒùÔº researchers have discovered a mechanism through which mitochondria, the energy factory of our body’s cells, play a role in preventing cells from dying when the cells are deprived of nutrients – a finding that points to a potential target for next-generation cancer drugs.</p> <p>The research, published in Molecular Cell, builds on previous work by Æ»¹ûÒùÔº professor Nahum Sonenberg, one of the senior authors of the new study.</p> Fri, 22 Sep 2017 14:41:40 +0000 shawn.hayward@mcgill.ca 2755 at /neuro /neuro/parkinsons-autoimmune-disease <p>A team of scientists led by Dr. Michel Desjardins from the University of Montreal and Dr. Heidi McBride from the Montreal Neurological Institute and Hospital (MNI) at Æ»¹ûÒùÔº have discovered that two genes associated with Parkinson's disease (PD) are key regulators of the immune system, providing direct evidence linking Parkinson's to autoimmune disease.</p> <p>Using both cellular and mouse models, the team has shown that proteins produced by the two genes, known as PINK1 and Parkin, are required to prevent cells from being detected and attacked by the immune system.</p> Mon, 27 Jun 2016 14:04:13 +0000 shawn.hayward@mcgill.ca 2104 at /neuro /neuro/article/focus-mitochondria The cell’s power source could be key to neurodegenerative diseases like Parkinson’s disease and ALS Tue, 18 Sep 2018 18:59:44 +0000 Victor Swoboda 3157 at /neuro