Le Laboratoire de recherche sur le cerveau et la cognition est dirig茅 par R. Nathan Spreng, professeur agr茅g茅 au D茅partement de neurologie et neurochirurgie de l'Universit茅 苹果淫院. On y explore la dynamique de r茅seaux neuronaux d鈥檈nvergure et leur r么le dans la cognition. Les 茅tudes actuelles concernent l鈥檃ttention, la m茅moire, le contr么le cognitif et la cognition sociale, ainsi que les r茅seaux du cerveau en interaction qui les soutiennent. Nous participons activement au d茅veloppement et 脿 la mise en application d鈥檃pproches statistiques 脿 variables multiples et ax茅es sur des r茅seaux, en vue d鈥櫭﹙aluer la structure du cerveau, sa connectivit茅 et l鈥檃ctivit茅 c茅r茅brale. Notre but est de mieux comprendre les propri茅t茅s des r茅seaux c茅r茅braux qui sous-tendent les processus cognitifs 脿 mesure qu鈥檌ls changent au cours de la vie 脿 l鈥櫭﹖at normal et pathologique.
S茅lection de publications听:
Schmitz, T.W. & Spreng, R.N. (2016). Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer鈥檚 pathology.听Nature Communications, 7, 13249.
Turner, G.R. & Spreng, R.N. (2015). Prefrontal engagement and reduced default network suppression co-occur and are dynamically coupled in older adults: The default 鈥� executive coupling hypothesis of aging.听Journal of Cognitive Neuroscience, 27, 2462-2476.
Spreng, R.N., DuPre, E., Selarka, D., Garcia, J., Gojkovic, S., Mildner, J., Luh, W.-M. & Turner, G.R. (2014). Goal-congruent default network activity facilitates cognitive control.听Journal of Neuroscience, 34, 14108-14111.
Andrews-Hanna, J.R., Smallwood, J. & Spreng, R.N. (2014). The default network and self-generated thought: Component processes, dynamic control, and clinical relevance.听Annals of the New York Academy of Sciences, 1316, 29-52.
Spreng, R.N., Sepulcre, J., Turner, G.R., Stevens, W.D. & Schacter, D.L. (2013). Intrinsic architecture underlying the relations among the default, dorsal attention, and frontoparietal control networks of the human brain.听Journal of Cognitive Neuroscience, 25, 74-86.
Spreng, R.N., Stevens, W.D., Chamberlain, J., Gilmore, A.W. & Schacter, D.L. (2010). Default network activity, coupled with the frontoparietal control network, supports goal-directed cognition.NeuroImage, 53, 303-317.
Spreng, R.N., Mar, R.A. & Kim, A.S.N. (2009). The common neural basis of autobiographical memory, prospection, navigation, theory of mind and the default mode: A quantitative meta-analysis.听Journal of Cognitive Neuroscience, 21, 489-510.听
