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Edward Ruthazer, PhD

Edward Ruthazer, PhD
Contact Information
Phone: 
514-398-4022
Email address: 
ed.ruthazer [at] mcgill.ca
Hospital title: 
James Æ»¹ûÒùÔº Professor
Biography: 

Edward Ruthazer is the recipient of a Tier II Canada Research Chair, a FRQS chaire de recherche, and a James Æ»¹ûÒùÔº Professorship. He is also the Director of the Integrated Program in Neuroscience graduate program at Æ»¹ûÒùÔº with about 600 full-time students.

The Ruthazer lab uses in vivo multiphoton microscopy and electrophysiology to study the development of topographic maps in the visual systems of zebrafish and Xenopus tadpoles, powerful animal models for live imaging. In particular, Dr. Ruthazer is interested in the influence of neural activity and early experience on the morphology and connectivity of the individual neurons that make up these neural maps.Ìý He also studies how glial cells and gliotransmitters interact with neurons in the developing nervous system to modulate the structural and functional plasticity of circuits.ÌýIn addition to studying these key events and molecular players in CNS development, the lab is interested in developing novel imaging and electrophysiology techniques for the study of neuronal connectivity and intracellular signalling.

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Selected publications: 

Van Horn, M.R., Strasser, A., Miraucourt, L.S., Pollegioni, L. and Ruthazer, E.S. (2017)ÌýÌýJ Neurosci,Ìý37: 6277-88.

Rahman, T.N., Munz, M., Kutsarova, E., Bilash, O.M. and Ruthazer, E.S. (2020)ÌýÌýPNAS,Ìý117: 10636-10638.

Kesner, P., Schohl, A., Warren, E., Ma, F. and Ruthazer, E.S (2020)ÌýÌýCell Reports,Ìý32: 107955.

Lim, T.K. and Ruthazer, E.S. (2021)ÌýÌýeLife,Ìý10:e62167.

Li, V.J. Schohl, A., Ruthazer, E.S. (2022)Ìý.ÌýPNAS,Ìý119 (8) e2107899119.

Research areas: 
Neural Circuits
Neurodevelopmental Disorders
Neuroimmunological Diseases

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The Neuro (Montreal Neurological Institute-Hospital)Ìýis a bilingual academic healthcare institution. We are aÌýÆ»¹ûÒùÔº research and teaching institute; delivering high-quality patient care, as part of the Neuroscience Mission of the Æ»¹ûÒùÔº Health Centre.ÌýWe areÌýproud to be a Killam Institution, supported by the Killam Trusts.

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