/channels/taxonomy/term/9307/all en /channels/channels/news/how-turn-specific-genes-and-334623 <p>Type 1 diabetes, rheumatoid arthritis, and cancer are just some of the disorders associated with specific genes not “turning on” and “turning off” as they should. By using new CRISPR/Cas9 genome editing technology, in a recent paper in <a href="https://www.nature.com/articles/s41467-021-25991-9/metrics"><i>Nature Communications</i></a><i>, </i>ƻ����Ժ researchers have described a new technique that scientists across the world can potentially use to explore novel ways of treating diseases associated with dysregulation in DNA methylation.</p> Tue, 09 Nov 2021 15:19:08 +0000 webfull 174578 at /channels /channels/news/early-life-adversity-affects-broad-regions-brain-dna-218498 <p><span>Early life experience results in a broad change in the way our DNA is “epigenetically” chemically marked in the brain by a coat of small chemicals called methyl groups, according to researchers at ƻ����Ժ. A group of researchers led by Prof. Moshe Szyf, a professor of Pharmacology and Therapeutics in the Faculty of Medicine, and research scientists at the Douglas Institute have discovered a remarkable similarity in the way the DNA in human brains and the DNA in animal brains respond to early life adversity. The finding suggests an evolutionary conserved mechanism of response to early life adversity affecting a large number of genes in the genome. </span></p> <div><span><span> Wed, 10 Oct 2012 16:41:26 +0000 webfull 87665 at /channels /channels/news/chronic-pain-alters-dna-marking-brain-225012 <div><span><span><span>Injuries that result in chronic pain, such as limb injuries, and those unrelated to the brain are associated with epigenetic changes in the brain which persist months after the injury, according to researchers at ƻ����Ժ. Epigenetics explores how the environment – including diet, exposure to contaminants and social conditions such as poverty – can have a long-term impact on the activity of our genes. Thu, 14 Feb 2013 15:25:08 +0000 webfull 94752 at /channels /channels/news/honey-i-shrunk-ants-how-environment-controls-size-243448 <p>Until now scientists have believed that the variations in traits such as our height, skin colour, tendency to gain weight or not, intelligence, tendency to develop certain diseases, etc., all of them traits that exist along a continuum, were a result of both genetic and environmental factors. But they didn’t know how exactly these things worked together. By studying ants, ƻ����Ժ researchers have identified a key mechanism by which environmental (or epigenetic) factors influence the expression of all of these traits, (along with many more). Wed, 11 Mar 2015 11:05:19 +0000 webfull 108724 at /channels /channels/news/chronic-pain-changes-our-immune-systems-258156 <p><em><strong>By Cynthia Lee</strong></em><br /><strong><a href="/newsroom">Newsroom</a></strong></p> <p>Chronic pain may reprogram the way genes work in the immune system, according to a new study by ƻ����Ժ researchers published in the journal <em>Scientific Reports</em>.  </p> Thu, 28 Jan 2016 11:39:36 +0000 webfull 115586 at /channels