mitochondria /channels/taxonomy/term/9158/all en Clarus Therapeutics and Æ»¹ûÒùÔº Announce Licensing Agreement to Develop and Commercialize Technology to Treat Coenzyme-Q10 Deficiencies /channels/channels/news/clarus-therapeutics-and-mcgill-university-announce-licensing-agreement-develop-and-commercialize-333414 <p><em>Agreement to accelerate development of potential treatments for rare, endocrine, metabolic, and neurological conditions associated with primary and secondary ubiquinone deficiencies which belong to the wider class of mitochondrial diseases | An estimated 1 in 5,000 adults worldwide has a mitochondrial disease | Clarus to pay Æ»¹ûÒùÔº $350,000 upfront and up to $10.5 million in potential development and regulatory milestones</em></p> Thu, 16 Sep 2021 13:12:57 +0000 webfull 173130 at /channels Mitochondria drive cell survival in times of need /channels/channels/news/mitochondria-drive-cell-survival-times-need-270560 <h2>Discovery points to possible target for cancer drugs</h2> <p>Æ»¹ûÒùÔº researchers have discovered a mechanism through which mitochondria, the energy factory of our body’s cells, play a role in preventing cells from dying when the cells are deprived of nutrients – a finding that points to a potential target for next-generation cancer drugs.</p> <p>The research, published in Molecular Cell, builds on previous work by Æ»¹ûÒùÔº professor Nahum Sonenberg, one of the senior authors of the new study.</p> Fri, 22 Sep 2017 14:41:42 +0000 webfull 131372 at /channels Scientists discover gene behind rare disorders /channels/news/scientists-discover-gene-behind-rare-disorders-218470 <h4>International study with researchers at The Neuro reveals links with other neurodegenerative diseases</h4> <p>MONTREAL, October 9, 2012  - Scientists at the Montreal Neurological Institute and Hospital – The Neuro,  Æ»¹ûÒùÔº working with a team at Oxford University have uncovered the genetic defect underlying a group of rare genetic disorders. </p> Tue, 09 Oct 2012 14:07:58 +0000 webfull 87617 at /channels Unleashing the watchdog protein /channels/news/unleashing-watchdog-protein-226719 <h3>Research opens door to<b> </b>new drug therapies for<b> </b>Parkinson’s disease</h3> Thu, 09 May 2013 18:38:16 +0000 webfull 96637 at /channels Popular antioxidant likely ineffective, study finds /channels/news/popular-antioxidant-likely-ineffective-study-finds-243263 <p>The popular dietary supplement ubiquinone, also known as Coenzyme Q<sub>10</sub>, is widely believed to function as an antioxidant, protecting cells against damage from free radicals. But a new study by scientists at Æ»¹ûÒùÔº finds that ubiquinone is not a crucial antioxidant -- and that consuming it is unlikely to provide any benefit. Fri, 06 Mar 2015 14:56:04 +0000 webfull 108543 at /channels Researchers open new path of discovery in Parkinson’s disease /channels/channels/news/researchers-open-new-path-discovery-parkinsons-disease-261508 <p>A team of scientists led by Dr. Michel Desjardins from the University of Montreal and Dr. Heidi McBride from the Montreal Neurological Institute and Hospital (MNI) at Æ»¹ûÒùÔº have discovered that two genes associated with Parkinson's disease (PD) are key regulators of the immune system, providing direct evidence linking Parkinson's to autoimmune disease.</p> <p>Using both cellular and mouse models, the team has shown that proteins produced by the two genes, known as PINK1 and Parkin, are required to prevent cells from being detected and attacked by the immune system.</p> Mon, 27 Jun 2016 14:04:15 +0000 webfull 119613 at /channels