/channels/taxonomy/term/2452/all en /channels/channels/news/childhood-trauma-increases-risk-chronic-pain-adulthood-353822 <p><!-- x-tinymce/html --></p> <p>Physical, sexual, or emotional abuse, or neglect, either alone or combined with other types of childhood trauma, increases the risk of chronic pain and related disability in adulthood, according to new research. The findings from an international team of experts, including several ƻ����Ժ researchers, underscore the urgency of addressing adverse childhood experiences (ACEs) – potentially traumatic events that occur before 18 years of age – and taking steps to mitigate their long-term impact on people’s health.  </p> Wed, 20 Dec 2023 21:08:38 +0000 webfull 195966 at /channels /channels/channels/news/new-nprc-reading-lists-351718 <p>The Neuro-Patient Resource has created reading lists for each of the Neuro's outpatient clinics. Come borrow the books in room 354!</p> <p>Download the PDF version of a reading list below: </p> <p><a href="/infoneuro/files/infoneuro/als_1.pdf">Reading list about <strong>Amyotrophic lateral sclerosis</strong> </a></p> <p><a href="/infoneuro/files/infoneuro/tumours_2.pdf">Reading list about <strong>Brain tumours</strong></a></p> Fri, 06 Oct 2023 16:43:49 +0000 webfull 193635 at /channels /channels/channels/news/new-model-identify-and-predict-chronic-pain-349138 <p>Chronic pain is a complex condition that affects millions of individuals worldwide and understanding its causes and predicting its trajectory remains difficult. However, findings from <a href="https://www.nature.com/articles/s41591-023-02430-4">a recent ƻ����Ժ-led study published in <i>Nature Medicine</i></a> could improve the understanding and management of chronic pain. The researchers developed a model that can predict one’s likelihood of developing chronic pain as well as the severity and spread of that pain.</p> Thu, 20 Jul 2023 16:18:01 +0000 webfull 190604 at /channels /channels/channels/event/aqdc-la-parole-aux-etudiants-chercheurs-peur-de-bouger-et-douleur-chronique-348656 <p><strong>This event is in French only.</strong></p> Thu, 08 Jun 2023 15:09:52 +0000 webfull 190036 at /channels /channels/channels/event/aqdc-la-parole-aux-etudiants-chercheurs-de-la-cellule-au-traitement-de-la-douleur-french-only-348094 <p>Webinaire de l'Association québécoise de la douleur chronique présenté par Claudie Beaulieu et Laurie Côté, avec Alice Wagenaar à l'animation.</p> Fri, 28 Apr 2023 14:49:25 +0000 webfull 189390 at /channels /channels/channels/news/no-pain-no-gain-how-brain-chooses-between-pain-and-profit-340351 <p>Imagine having to choose over and over between what you enjoy doing and the pain that it might cause you, whether physical or emotional. If you live with conditions such as depression, anxiety, or chronic pain, you are probably familiar with making these difficult choices on a daily or weekly basis. But surprisingly little is known about which areas of the brain are involved in decisions of this kind.</p> Wed, 20 Jul 2022 14:13:15 +0000 webfull 180952 at /channels /channels/channels/news/sex-bias-pain-research-322305 <p>It is increasingly clear that male and female humans and rodents process pain in different ways. And that there are important differences in the underlying mechanisms involved at genetic, molecular, cellular, and physiological levels. Despite this fact, according to a review paper from ƻ����Ժ published today in <a href="https://www.nature.com/articles/s41583-020-0310-6"><i>Nature Reviews Neuroscience</i></a>, most pain research remains overwhelmingly based on the study of male rodents, continuing to test hypotheses derived from earlier experiments on males.</p> Thu, 21 May 2020 14:07:31 +0000 webfull 160843 at /channels /channels/channels/news/pain-induced-changes-brains-opioid-system-may-explain-limited-effectiveness-opioid-therapy-chronic-287353 <div><span>Pain-induced changes in the brain’s opioid receptor system may explain the limited effectiveness of opioid therapy in chronic pain and may play a role in the depression that often accompanies it, according to a study from the NIH’s Intramural Research Program and ƻ����Ժ. Although the study, published in the journal Pain, was conducted in rats, and the results of animal studies may not be directly applicable to people, the findings provide new insights into how the brain may respond to pain and opioids.</span></div> <div> </div> Sun, 27 May 2018 16:19:58 +0000 webfull 138182 at /channels /channels/channels/news/newly-discovered-pathway-pain-processing-could-lead-new-treatments-269285 <p>The discovery of a new biological pathway involved in pain processing offers hope of using existing cancer drugs to replace the use of opioids in chronic pain treatment, according to scientists at ƻ����Ժ.</p> <p>Because many therapeutic options, such as opioids, for patients with chronic pain carry the risk of addiction and undesirable side effects, this breakthrough offers promising lines of research into chronic pain treatment, says Luda Diatchenko, professor at ƻ����Ժ’s Faculty of Dentistry and co-lead author of the new study</p> Tue, 08 Aug 2017 14:20:16 +0000 webfull 129561 at /channels /channels/news/chronic-pain-changes-our-immune-systems-258156 <p><em><strong>By Cynthia Lee</strong></em><br /><strong><a href="/newsroom">Newsroom</a></strong></p> <p>Chronic pain may reprogram the way genes work in the immune system, according to a new study by ƻ����Ժ researchers published in the journal <em>Scientific Reports</em>.  </p> Thu, 28 Jan 2016 11:39:36 +0000 webfull 115586 at /channels /channels/news/location-may-be-key-effectively-controlling-pain-258233 <p><em><strong>By Cynthia Lee</strong></em></p> <p><a href="//www.mcgill.ca/newsroom/">Newsroom</a></p> <p>In real estate, location is key. It now seems the same concept holds true when it comes to stopping pain. New research published in <em>Nature Communications</em> indicates that the location of receptors that transmit pain signals<em> is</em> important in how big or small a pain signal will be -- and therefore how effectively drugs can block those signals.</p> Wed, 03 Feb 2016 15:06:22 +0000 webfull 115726 at /channels /channels/news/pain-curbs-sex-drive-female-mice-not-males-235376 <p>“Not tonight, dear, I have a headache.” Generally speaking, that line is attributed to the wife in a couple, implying that women’s sexual desire is more affected by pain than men’s.</p> <p> Tue, 22 Apr 2014 21:09:29 +0000 webfull 102507 at /channels /channels/channels/news/brighter-prospects-chronic-pain-260442 <h2>Researchers use optogenetics to produce pain relief by shutting off neurons with light</h2> <p>The potential of light as a non-invasive, highly-focused alternative to pain medication was made more apparent thanks to research conducted by scientists at the Montreal Neurological Institute and Hospital of ƻ����Ժ and the ƻ����Ժ Health Centre.</p> Wed, 20 Apr 2016 13:37:23 +0000 webfull 118331 at /channels /channels/news/new-hope-fight-against-pain-242448 <p>An international study led by scientists at ƻ����Ժ reports, for the first time, that drugs that selectively target the melatonin MT2 receptor represent a novel class of analgesic drugs that could be used to treat patients with neuropathic pain. Tue, 17 Feb 2015 16:19:54 +0000 webfull 108187 at /channels /channels/news/how-insulin-calms-brain-activity-253761 <p>Insulin has long been known as the hormone which controls the body’s sugar levels: humans who lack or are insensitive to insulin develop diabetes. Although insulin is also made and released in the brain, its effects there have remained unclear.</p> <p> Tue, 30 Jun 2015 21:01:04 +0000 webfull 110970 at /channels